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NPY Y2 antagonist 1 (compound 36) is a potent, soluble pyridine analog. In summary, highly promising high-throughput screening hits were extensively explored for structure-activity relationships and a range of potency-enhancing modifications were identified. A potent, soluble, and selective NPY Y2 antagonist 36 was discovered that is amenable to in vitro screening studies. In vivo studies on this molecule will be published in due course.

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NPY Y2 antagonist 1 Chemical Structure

NPY Y2 antagonist 1 Chemical Structure

CAS No. : 1185845-15-1

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Description

NPY Y2 antagonist 1 (compound 36) is a potent, soluble pyridine analog. In summary, highly promising high-throughput screening hits were extensively explored for structure-activity relationships and a range of potency-enhancing modifications were identified. A potent, soluble, and selective NPY Y2 antagonist 36 was discovered that is amenable to in vitro screening studies. In vivo studies on this molecule will be published in due course.

Molecular Weight

493.00

Formula

C27H29ClN4O3
CAS No.
SMILES

O=C(N1CCN(CC1)C2=CC=C(NC(C(C)(C)C3=CC=CC=C3)=O)C=C2Cl)C4=NC=CC=C4OC
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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NPY Y2 antagonist 1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NPY Y2 antagonist 11185845-15-1OthersInhibitorinhibitorinhibit

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