2. Epigenetics
  3. Histone Acetyltransferase
  4. NSC 698600

NSC 698600 is a potent PCAF inhibitor, with IC50 of 6.51 µM (PCAF/H31-21). NSC 698600 exhibits good activity of inhibiting the proliferation of cancer cells.

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NSC 698600 Chemical Structure

NSC 698600 Chemical Structure

CAS No. : 908069-17-0

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Based on 1 publication(s) in Google Scholar

NSC 698600 Related Antibodies

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Description

NSC 698600 is a potent PCAF inhibitor, with IC50 of 6.51 µM (PCAF/H31-21). NSC 698600 exhibits good activity of inhibiting the proliferation of cancer cells[1].

IC50 & Target

IC50: 6.51 µM (PCAF/H31-21)[1].
Cellular Effect
Cell Line Type Value Description References
SK-N-SH GI50
12.2 μM
Compound: NSC-698600
Growth inhibition of human SK-N-SH cells by CellTiter-96 Aqueous Non-radioactive cell proliferation assay
Growth inhibition of human SK-N-SH cells by CellTiter-96 Aqueous Non-radioactive cell proliferation assay
[PMID: 21353783]
In Vitro

NSC 698600 (25 µM; 72 h) exhibits antiproliferative effect to SK-N-SH and HCT116 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

NSC 698600 Related Antibodies

Cell Proliferation Assay[1]

Cell Line: SK-N-SH, HCT116 cells
Concentration: 25 µM
Incubation Time: 72 h
Result: Showed antiproliferative effect to SK-N-SH and HCT116 cells with GI50 of 12.2 µM and growth inhibition of 40%, respectively.
Molecular Weight

272.32

Formula

C14H12N2O2S
CAS No.
SMILES

O=C1C2=CC(C)=CN=C2SN1C3=CC=C(C=C3)OC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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NSC 698600 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NSC 698600908069-17-0NSC698600NSC-698600Histone AcetyltransferaseHATsHATPCAFpyridoisothiazolonesHAT inhibitorcancerSK-N-SHHCT116Inhibitorinhibitorinhibit

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HY-147289
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