1. GPCR/G Protein
  2. Bradykinin Receptor
  3. NVP-SAA164

NVP-SAA164 is an orally active nonpeptide kinin B1 receptor antagonist. NVP-SAA164 reverses CFA (Complete Freund's adjuvant) (HY-153808)-induced mechanical hyperalgesia and desArg10KD-induced hyperalgesia in hB1-KI mice, and is inactive in a model of inflammatory pain in wild-type mice.

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NVP-SAA164 Chemical Structure

NVP-SAA164 Chemical Structure

CAS No. : 312722-60-4

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Description

NVP-SAA164 is an orally active nonpeptide kinin B1 receptor antagonist. NVP-SAA164 reverses CFA (Complete Freund's adjuvant) (HY-153808)-induced mechanical hyperalgesia and desArg10KD-induced hyperalgesia in hB1-KI mice, and is inactive in a model of inflammatory pain in wild-type mice[1].

Molecular Weight

659.84

Formula

C36H45N5O5S

CAS No.
SMILES

O=C(N1CCOCC1)C2=CC(S(=O)(N3CCC(CC3)C(N4CCN(CC4)C)=O)=O)=CC=C2NCC(C5=CC=CC=C5)C6=CC=CC=C6

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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NVP-SAA164 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
NVP-SAA164
Cat. No.:
HY-15041
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