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  4. Nε-(Carboxymethyl)-L-lysine

Nε-(Carboxymethyl)-L-lysine  (Synonyms: CML; N6-(Carboxymethyl)-L-lysine; Nε-(1-Carboxymethyl)-L-lysine)

Cat. No.: HY-W286743 Purity: ≥95.0%
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Nε-(Carboxymethyl)-L-lysine (CML) is a unique post-translational modification (PTM) of proteins that is generated by the non-enzymatic glycation of lysine residues. Nε-(Carboxymethyl)-L-lysine is a relatively recently discovered modification, and has been found to be a major component of the advanced glycation endproducts (AGEs) found in multiple human diseases, such as diabetes, Alzheimer’s disease, and cancer.

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Nε-(Carboxymethyl)-L-lysine Chemical Structure

Nε-(Carboxymethyl)-L-lysine Chemical Structure

CAS No. : 5746-04-3

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1 mg USD 170 In-stock
5 mg USD 480 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Nε-(Carboxymethyl)-L-lysine:

Nε-(Carboxymethyl)-L-lysine Related Antibodies

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Description

Nε-(Carboxymethyl)-L-lysine (CML) is a unique post-translational modification (PTM) of proteins that is generated by the non-enzymatic glycation of lysine residues. Nε-(Carboxymethyl)-L-lysine is a relatively recently discovered modification, and has been found to be a major component of the advanced glycation endproducts (AGEs) found in multiple human diseases, such as diabetes, Alzheimer’s disease, and cancer[1].

Molecular Weight

204.22

Formula

C8H16N2O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C(CCNCC(=O)O)C[C@@H](C(=O)O)N
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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Nε-(Carboxymethyl)-L-lysine Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Nε-(Carboxymethyl)-L-lysine5746-04-3CML N6-(Carboxymethyl)-L-lysine Nε-(1-Carboxymethyl)-L-lysineBiochemical Assay ReagentsAdvanced Glycation End-product (AGE)GlycationProtein ModificationDiabetes ComplicationsInhibitorinhibitorinhibit

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