2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Nε,Nε,Nε-Trimethyllysine-d9 chloride

Nε,Nε,Nε-Trimethyllysine-d9 chloride  (Synonyms: Ne-(Trimethyl)-L-lysine-d9 chloride; H-Lys(Me)3-OH-d9 chloride)

Cat. No.: HY-N7404S Purity: ≥95.0%
COA Handling Instructions

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Nε,Nε,Nε-Trimethyllysine-d9 (chloride) is the deuterium labeled Nε,Nε,Nε-Trimethyllysine (chloride)[1]. Nε,Nε,Nε-Trimethyllysine chloride serves as a precursor for gut flora-dependent formation of N,N,N-trimethyl-5-aminovaleric acid (TMAVA)[2].

For research use only. We do not sell to patients.

Nε,Nε,Nε-Trimethyllysine-d<sub>9</sub> chloride Chemical Structure

Nε,Nε,Nε-Trimethyllysine-d9 chloride Chemical Structure

Size Price Stock Quantity
1 mg USD 240 In-stock
5 mg USD 620 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Nε,Nε,Nε-Trimethyllysine-d9 chloride:

Nε,Nε,Nε-Trimethyllysine-d9 chloride Related Antibodies

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Description

Nε,Nε,Nε-Trimethyllysine-d9 (chloride) is the deuterium labeled Nε,Nε,Nε-Trimethyllysine (chloride)[1]. Nε,Nε,Nε-Trimethyllysine chloride serves as a precursor for gut flora-dependent formation of N,N,N-trimethyl-5-aminovaleric acid (TMAVA)[2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Nε,Nε,Nε-Trimethyllysine-d9 chloride Related Antibodies
Molecular Weight

233.78

Formula

C9H12D9ClN2O2
Unlabeled CAS

55528-53-5
Appearance

Solid

Color

White to off-white

SMILES

OC([C@@H](N)CCCC[N+](C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])=O.[Cl-]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 250 mg/mL (1069.38 mM; Need ultrasonic)

H2O : 250 mg/mL (1069.38 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.2775 mL 21.3876 mL 42.7753 mL
5 mM 0.8555 mL 4.2775 mL 8.5551 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥95.0%

COA (251 KB) HNMR (136 KB) MS (81 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / H2O 1 mM 4.2775 mL 21.3876 mL 42.7753 mL 106.9381 mL
5 mM 0.8555 mL 4.2775 mL 8.5551 mL 21.3876 mL
10 mM 0.4278 mL 2.1388 mL 4.2775 mL 10.6938 mL
15 mM 0.2852 mL 1.4258 mL 2.8517 mL 7.1292 mL
20 mM 0.2139 mL 1.0694 mL 2.1388 mL 5.3469 mL
25 mM 0.1711 mL 0.8555 mL 1.7110 mL 4.2775 mL
30 mM 0.1426 mL 0.7129 mL 1.4258 mL 3.5646 mL
40 mM 0.1069 mL 0.5347 mL 1.0694 mL 2.6735 mL
50 mM 0.0856 mL 0.4278 mL 0.8555 mL 2.1388 mL
60 mM 0.0713 mL 0.3565 mL 0.7129 mL 1.7823 mL
80 mM 0.0535 mL 0.2673 mL 0.5347 mL 1.3367 mL
100 mM 0.0428 mL 0.2139 mL 0.4278 mL 1.0694 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Nε,Nε,Nε-Trimethyllysine-d9 chloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Nε,Nε,Nε-Trimethyllysine-d9Ne-(Trimethyl)-L-lysine-d9H-Lys(Me)3-OH-d9Endogenous MetaboliteInhibitorinhibitorinhibit

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