2. GPCR/G Protein Neuronal Signaling Metabolic Enzyme/Protease
  3. mGluR Endogenous Metabolite
  4. O-Phospho-L-serine-13C3,15N

O-Phospho-L-serine-13C3,15N  (Synonyms: L-Serine O-phosphate-13C3,15N; L-SOP-13C3,15N)

Cat. No.: HY-15129S Purity: 99.19%
SDS COA Handling Instructions

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O-Phospho-L-serine-13C3,15N is the 13C- and 15N-labeled O-Phospho-L-serine. O-Phospho-L-serine is the immediate precursor to L-serine in the serine synthesis pathway, and an agonist at the group III mGluR receptors (mGluR4, mGluR6, mGluR7, and mGluR8); O-Phospho-L-serine also acts as a weak antagonist for mGluR1 and a potent antagonist for mGluR2[1].

For research use only. We do not sell to patients.

O-Phospho-L-serine-<sup>13</sup>C<sub>3</sub>,<sup>15</sup>N Chemical Structure

O-Phospho-L-serine-13C3,15N Chemical Structure

CAS No. : 2734706-69-3

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500 μg USD 848 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of O-Phospho-L-serine-13C3,15N:

O-Phospho-L-serine-13C3,15N Related Antibodies

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Description

O-Phospho-L-serine-13C3,15N is the 13C- and 15N-labeled O-Phospho-L-serine. O-Phospho-L-serine is the immediate precursor to L-serine in the serine synthesis pathway, and an agonist at the group III mGluR receptors (mGluR4, mGluR6, mGluR7, and mGluR8); O-Phospho-L-serine also acts as a weak antagonist for mGluR1 and a potent antagonist for mGluR2[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

O-Phospho-L-serine-13C3,15N Related Antibodies
Molecular Weight

189.04

Formula

13C3H8 15NO6P
CAS No.
Unlabeled CAS

407-41-0
Appearance

Solid

Color

Off-white to light yellow

SMILES

OP(O[13CH2][13C@H]([15NH2])[13C](O)=O)(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 25 mg/mL (132.25 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.2899 mL 26.4494 mL 52.8989 mL
5 mM 1.0580 mL 5.2899 mL 10.5798 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.19%

SDS (252 KB)

COA (251 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 5.2899 mL 26.4494 mL 52.8989 mL 132.2471 mL
5 mM 1.0580 mL 5.2899 mL 10.5798 mL 26.4494 mL
10 mM 0.5290 mL 2.6449 mL 5.2899 mL 13.2247 mL
15 mM 0.3527 mL 1.7633 mL 3.5266 mL 8.8165 mL
20 mM 0.2645 mL 1.3225 mL 2.6449 mL 6.6124 mL
25 mM 0.2116 mL 1.0580 mL 2.1160 mL 5.2899 mL
30 mM 0.1763 mL 0.8816 mL 1.7633 mL 4.4082 mL
40 mM 0.1322 mL 0.6612 mL 1.3225 mL 3.3062 mL
50 mM 0.1058 mL 0.5290 mL 1.0580 mL 2.6449 mL
60 mM 0.0882 mL 0.4408 mL 0.8816 mL 2.2041 mL
80 mM 0.0661 mL 0.3306 mL 0.6612 mL 1.6531 mL
100 mM 0.0529 mL 0.2645 mL 0.5290 mL 1.3225 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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O-Phospho-L-serine-13C3,15N Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

O-Phospho-L-serine-13C3,15N2734706-69-3L-Serine O-phosphate-13C3,15NL-SOP-13C3,15NmGluREndogenous MetaboliteMetabotropic glutamate receptorsInhibitorinhibitorinhibit

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