2. Metabolic Enzyme/Protease
  3. Phospholipase
  4. Ochnaflavone

Ochnaflavone is an inhibitor of IIA-type secretory phospholipase A2 (sPLA2-IIA) with an IC50 of 3.45 µM. Ochnaflavone exhibits significant anti-inflammatory and liver-protective effects, capable of inhibiting the degradation of phosphatidylethanolamine (PE) and lipid peroxidation induced by carbon tetrachloride (CCl4) in rat liver, with an IC50 of 7.16 µM for lipid peroxidation. Ochnaflavone can be used in research on liver damage and inflammatory diseases.

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Ochnaflavone Chemical Structure

Ochnaflavone Chemical Structure

CAS No. : 50276-96-5

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Ochnaflavone Related Antibodies

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Description

Ochnaflavone is an inhibitor of IIA-type secretory phospholipase A2 (sPLA2-IIA) with an IC50 of 3.45 µM. Ochnaflavone exhibits significant anti-inflammatory and liver-protective effects, capable of inhibiting the degradation of phosphatidylethanolamine (PE) and lipid peroxidation induced by carbon tetrachloride (CCl4) in rat liver, with an IC50 of 7.16 µM for lipid peroxidation. Ochnaflavone can be used in research on liver damage and inflammatory diseases[1].

IC50 & Target

sPLA2

3.45 μM (IC50)

Molecular Weight

538.46

Formula

C30H18O10
CAS No.
SMILES

O=C1C=C(C2=CC=C(OC3=CC(C4=CC(C5=C(O)C=C(O)C=C5O4)=O)=CC=C3O)C=C2)OC6=CC(O)=CC(O)=C16
Initial Source
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Ochnaflavone Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ochnaflavone50276-96-5PhospholipaseAnti-inflammatoryLiver-protectiveInhibitorinhibitorinhibit

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