2. Anti-infection
  3. Bacterial
  4. Ocotillone

Ocotillone ((24S)-20,24-Epoxy-25-hydroxydammaran-3-one) is a triterpenoids that can be isolated from the fruits of Dysoxylum richii. Ocotillone has antibacterial activities against P. aeruginosa and S. typhimurium without hemolytic activity.

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Ocotillone Chemical Structure

Ocotillone Chemical Structure

CAS No. : 35761-54-7

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Ocotillone Related Antibodies

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Description

Ocotillone ((24S)-20,24-Epoxy-25-hydroxydammaran-3-one) is a triterpenoids that can be isolated from the fruits of Dysoxylum richii. Ocotillone has antibacterial activities against P. aeruginosa and S. typhimurium without hemolytic activity[1].

Cellular Effect
Cell Line Type Value Description References
COLO 205 IC50
> 100 μM
Compound: 12
Cytotoxicity against human COLON205 cells after 48 hrs by MTT assay
Cytotoxicity against human COLON205 cells after 48 hrs by MTT assay
[PMID: 17346076]
HepG2 IC50
142 μM
Compound: 15, 24-epi-ocotillol
Cytotoxicity against human Hep G2 cells after 48 hrs by WST-8 assay
Cytotoxicity against human Hep G2 cells after 48 hrs by WST-8 assay
[PMID: 15730243]
K562 IC50
> 100 μM
Compound: 12
Cytotoxicity against human K562 cells after 48 hrs by MTT assay
Cytotoxicity against human K562 cells after 48 hrs by MTT assay
[PMID: 17346076]
K562/Adr IC50
> 100 μM
Compound: 12
Cytotoxicity against human doxorubicin-resistant K562/Adr cells after 48 hrs by MTT assay
Cytotoxicity against human doxorubicin-resistant K562/Adr cells after 48 hrs by MTT assay
[PMID: 17346076]
K562/Adr IC50
> 100 μM
Compound: 12
Cytotoxicity against human doxorubicin-resistant K562/Adr cells in presence of 1 uM doxorubicin after 48 hrs by MTT assay
Cytotoxicity against human doxorubicin-resistant K562/Adr cells in presence of 1 uM doxorubicin after 48 hrs by MTT assay
[PMID: 17346076]
KB IC50
> 100 μM
Compound: 12
Cytotoxicity against human KB cells after 48 hrs by MTT assay
Cytotoxicity against human KB cells after 48 hrs by MTT assay
[PMID: 17346076]
MCF7 IC50
> 100 μM
Compound: 12
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
[PMID: 17346076]
WI-38 IC50
2.4 μM
Compound: 15, 24-epi-ocotillol
Cytotoxicity against human WI 38 cells after 48 hrs by WST-8 assay
Cytotoxicity against human WI 38 cells after 48 hrs by WST-8 assay
[PMID: 15730243]
WI-38 VA13 IC50
199 μM
Compound: 15, 24-epi-ocotillol
Cytotoxicity against human VA13 cells after 48 hrs by WST-8 assay
Cytotoxicity against human VA13 cells after 48 hrs by WST-8 assay
[PMID: 15730243]
Molecular Weight

458.72

Formula

C30H50O3
CAS No.
SMILES

C[C@]12[C@@](CC[C@@]3([H])[C@]2(CC[C@]3([H])[C@]4(O[C@H](C(C)(O)C)CC4)C)C)([H])[C@@]5([C@@](C(C)(C(CC5)=O)C)([H])CC1)C
Structure Classification
Initial Source

Bifidobacterium richum
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Ocotillone Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ocotillone35761-54-7CabraleoneBacterialantibacterialinfectionInhibitorinhibitorinhibit

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