2. Immunology/Inflammation
  3. Toll-like Receptor (TLR)
  4. ODN 2088 sodium

ODN 2088 sodium is a potent TLR3, TLR7 and TLR9 inhibitor. ODN 2088 sodium shows no cytotoxic. ODN 2088 inhibits the release of IFN-α and IL-6.

For research use only. We do not sell to patients.

DNA, d(P-thio)(T-C-C-T-G-G-C-G-G-G-G-A-A-G-T), sodium salt

ODN 2088 sodium Chemical Structure

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1 mg USD 79 In-stock
5 mg USD 206 In-stock
10 mg USD 330 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of ODN 2088 sodium:

ODN 2088 sodium Related Antibodies

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TLR3 TLR8 TLR9 TLR2 TLR4 TLR7 TLR1 TLR6

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Description

ODN 2088 sodium is a potent TLR3, TLR7 and TLR9 inhibitor. ODN 2088 sodium shows no cytotoxic. ODN 2088 inhibits the release of IFN-α and IL-6[1][2][3].

Appearance

Solid

Color

White to off-white

SMILES

[ODN 2088 (sodium)]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : ≥ 25 mg/mL

*"≥" means soluble, but saturation unknown.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 90.41%

COA (244 KB) LCMS (797 KB)

Handling Instructions (2659 KB)
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ODN 2088 sodium Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ODN 2088ODN2088ODN-2088Toll-like Receptor (TLR)no cytotoxicIFN-αIL-6PBMCsB cellsInhibitorinhibitorinhibit

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Product Name:
ODN 2088 sodium
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HY-150738C
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