2. Immunology/Inflammation
  3. Toll-like Receptor (TLR)
  4. ODN 24991

ODN 24991, a guanine-modified inhibitory oligonucleotide (INH-ODN), is a TLR3, TLR7 and TLR9 (Toll-like receptor) inhibitor, and its parent is INH-ODN 2088. ODN 24991 disrupts TLR3-, TLR7- and TLR9-mediated immune cell immune responses. ODN 24991 sequence: 5'-C-C-T-G-G-C-c7rGm-G-G-G-3'.

The free form of the compound is prone to instability, it is advisable to consider the stable salt form (ODN 24991 sodium) that retains the same biological activity.

For research use only. We do not sell to patients.

DNA, d(P-thio)(C-C-T-G-G-C-c7rGm-G-G-G)

ODN 24991 Chemical Structure

CAS No. : 1682661-49-9

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Other Forms of ODN 24991:

ODN 24991 Related Antibodies

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Description

ODN 24991, a guanine-modified inhibitory oligonucleotide (INH-ODN), is a TLR3, TLR7 and TLR9 (Toll-like receptor) inhibitor, and its parent is INH-ODN 2088. ODN 24991 disrupts TLR3-, TLR7- and TLR9-mediated immune cell immune responses. ODN 24991 sequence: 5'-C-C-T-G-G-C-c7rGm-G-G-G-3'[1].

CAS No.
Appearance

Solid

Color

White to off-white

Sequence

DNA, d(P-thio)(C-C-T-G-G-C-c7rGm-G-G-G)
SMILES

[DNA, d(P-thio)(C-C-T-G-G-C-c7rGm-G-G-G)]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (Need ultrasonic)

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ODN 24991 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ODN 249911682661-49-9ODN24991ODN-24991Toll-like Receptor (TLR)TLR inhibitor,TLR3TLR7TLR9immune responseoligonucleotideInhibitorinhibitorinhibit

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HY-150746
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