2. Immunology/Inflammation
  3. CD20
  4. Ofatumumab

Ofatumumab is a fully human anti-CD20 monoclonal antibody that induces antibody-dependent cell-mediated cytotoxicity and complement-dependent cytotoxicity in CD20-expressing B lymphocytes.

For research use only. We do not sell to patients.

CAS No. : 679818-59-8

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Description

Ofatumumab is a fully human anti-CD20 monoclonal antibody that induces antibody-dependent cell-mediated cytotoxicity and complement-dependent cytotoxicity in CD20-expressing B lymphocytes[1].

Isotype

Human IgG1 kappa
Recommend Isotype Controls
Species

Human
Clinical Trial
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Ofatumumab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG1 kappa
Biological Activity
  • Ofatumumab has a significant ADCP effect on Raji cells in a dose-dependent manner.The EC50 for this effect is 24.00 and 25.15 ng/mL.
Purity & Documentation

Purity: ≥99.0%

SDS (251 KB)

COA (231 KB) SDS-PAGE (144 KB) SEC-HPLC (126 KB)

Inhibitory Antibodies User Guide (602 KB)
References
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Ofatumumab Related Classifications

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The dilution calculator equation

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ofatumumab679818-59-8CD20anti-CD20 monoclonal antibodyselectivecytotoxicitylysing B cellschronic lymphocytic leukaemiaInhibitorinhibitorinhibit

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