Ombuin

Cat. No.: HY-N3139 Purity: 98.96%: FAQs
Data Sheet SDS COA Handling Instructions

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Ombuin, isolated from Zanthoxylum armatum, displays broad spectrum antibacterial effect with MIC ranges from 125 to 500 μg/mL.

For research use only. We do not sell to patients.

Ombuin Chemical Structure

CAS No. : 529-40-8

Size	Price	Stock	Quantity
1 mg	USD 50	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 150	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 240	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
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Description

Ombuin, isolated from Zanthoxylum armatum, displays broad spectrum antibacterial effect with MIC ranges from 125 to 500 μg/mL^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	3.07 μM Compound: 5a	Anticancer activity against human A549 cells by HTS assay Anticancer activity against human A549 cells by HTS assay	[PMID: 25139569]
Calu-1	IC₅₀	> 50 μM Compound: 5a	Anticancer activity against human Calu1 cells by HTS assay Anticancer activity against human Calu1 cells by HTS assay	[PMID: 25139569]
HeLa	IC₅₀	1.49 μM Compound: 5a	Anticancer activity against human HeLa cells by HTS assay Anticancer activity against human HeLa cells by HTS assay	[PMID: 25139569]
HOP-62	IC₅₀	12.11 μM Compound: 5a	Anticancer activity against human HOP62 cells by HTS assay Anticancer activity against human HOP62 cells by HTS assay	[PMID: 25139569]
LOX IMVI	IC₅₀	> 50 μM Compound: 5a	Anticancer activity against human LOXIMVI cells by HTS assay Anticancer activity against human LOXIMVI cells by HTS assay	[PMID: 25139569]
M14	IC₅₀	4.29 μM Compound: 5a	Anticancer activity against human M14 cells by HTS assay Anticancer activity against human M14 cells by HTS assay	[PMID: 25139569]
NCI-H1299	IC₅₀	34.82 μM Compound: 5a	Anticancer activity against human H1299 cells by HTS assay Anticancer activity against human H1299 cells by HTS assay	[PMID: 25139569]
NCI-H157	IC₅₀	3.45 μM Compound: 5a	Anticancer activity against human NCI-H157 cells by HTS assay Anticancer activity against human NCI-H157 cells by HTS assay	[PMID: 25139569]
NCI-H1792	IC₅₀	3.36 μM Compound: 5a	Anticancer activity against human NCI-H1792 cells by HTS assay Anticancer activity against human NCI-H1792 cells by HTS assay	[PMID: 25139569]
NCI-H1944	IC₅₀	2.86 μM Compound: 5a	Anticancer activity against human NCI-H1944 cells by HTS assay Anticancer activity against human NCI-H1944 cells by HTS assay	[PMID: 25139569]
NCI-H460	IC₅₀	2.75 μM Compound: 5a	Anticancer activity against human H460 cells by HTS assay Anticancer activity against human H460 cells by HTS assay	[PMID: 25139569]
NCI-H522	IC₅₀	17.37 μM Compound: 5a	Anticancer activity against human NCI-H522 cells by HTS assay Anticancer activity against human NCI-H522 cells by HTS assay	[PMID: 25139569]

Molecular Weight

330.29

Formula

C₁₇H₁₄O₇

CAS No.

529-40-8

Appearance

Solid

Color

White to yellow

SMILES

O=C1C2=C(O)C=C(OC)C=C2OC(C3=CC(O)=C(OC)C=C3)=C1O

Structure Classification

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (302.76 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.0276 mL	15.1382 mL	30.2764 mL
5 mM	0.6055 mL	3.0276 mL	6.0553 mL
10 mM	0.3028 mL	1.5138 mL	3.0276 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 98.96%

Select Batch:

Data Sheet (269 KB) SDS (480 KB)

COA (249 KB) HNMR (178 KB) RP-HPLC (220 KB)

Handling Instructions (2659 KB)

References

[1]. Nooreen Z, et al. Characterization and evaluation of bioactive polyphenolic constituents from Zanthoxylum armatum DC., a traditionally used plant. Biomed Pharmacother. 2017 May;89:366-375. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.0276 mL	15.1382 mL	30.2764 mL	75.6911 mL
	5 mM	0.6055 mL	3.0276 mL	6.0553 mL	15.1382 mL
	10 mM	0.3028 mL	1.5138 mL	3.0276 mL	7.5691 mL
	15 mM	0.2018 mL	1.0092 mL	2.0184 mL	5.0461 mL
	20 mM	0.1514 mL	0.7569 mL	1.5138 mL	3.7846 mL
	25 mM	0.1211 mL	0.6055 mL	1.2111 mL	3.0276 mL
	30 mM	0.1009 mL	0.5046 mL	1.0092 mL	2.5230 mL
	40 mM	0.0757 mL	0.3785 mL	0.7569 mL	1.8923 mL
	50 mM	0.0606 mL	0.3028 mL	0.6055 mL	1.5138 mL
	60 mM	0.0505 mL	0.2523 mL	0.5046 mL	1.2615 mL
	80 mM	0.0378 mL	0.1892 mL	0.3785 mL	0.9461 mL
	100 mM	0.0303 mL	0.1514 mL	0.3028 mL	0.7569 mL

Ombuin Related Classifications

Infection

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ombuin529-40-8BacterialZanthoxylumarmatumbroadspectrumantibacterialInhibitorinhibitorinhibit

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Complete Stock Solution Preparation Table

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