ONO-6126

Cat. No.: HY-121491: FAQs
Data Sheet Handling Instructions

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ONO-6126 is a PDE4 inhibitor that can be used in research for asthma and chronic obstructive pulmonary disease.

For research use only. We do not sell to patients.

ONO-6126 Chemical Structure

CAS No. : 401519-28-6

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•Related Small Molecules:

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PDE1 PDE2 PDE3 PDE4 PDE5 PDE6 PDE7 PDE9 PDE10 PDE11 PDE12 PDE8 Autotaxin

Biological Activity
Purity & Documentation
References
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Description

ONO-6126 is a PDE4 inhibitor that can be used in research for asthma and chronic obstructive pulmonary disease^[1].

IC₅₀ & Target

PDE4

Molecular Weight

373.45

Formula

C₂₀H₂₇N₃O₄

CAS No.

401519-28-6

SMILES

N#CC1(CCN(CC1)CC(NO)=O)C2=CC=C(C(OC3CCCC3)=C2)OC

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Giembycz MA. Phosphodiesterase-4: selective and dual-specificity inhibitors for the therapy of chronic obstructive pulmonary disease. Proc Am Thorac Soc. 2005;2(4):326-33; discussion 340-1. [Content Brief]

ONO-6126 Related Classifications

Inflammation/Immunology

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ONO-6126401519-28-6ONO6126ONO 6126Phosphodiesterase (PDE)PDE4asthmachronic obstructive pulmonary diseaseInhibitorinhibitorinhibit

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