Ophiopogonin D (Standard)

Cat. No.: HY-N0515R Purity: ≥98%: FAQs
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Ophiopogonin D (Standard) is the analytical standard of Ophiopogonin D. This product is intended for research and analytical applications. Ophiopogonin D, isolated from the tubers of Ophiopogon japonicus, is a rare naturally occurring C29 steroidal glycoside. Ophiopogonin D is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation, IκBα down-regulation, intracellular Ca2+ overload and activation of pro-inflammatory cytokines by increasing the expression of CYP2J2/EETs and PPARα in human umbilical vein endothelial cells (HUVECs). Ophiopogonin D has been used to treat inflammatory and cardiovascular diseases for thousands of years.

For research use only. We do not sell to patients.

Ophiopogonin D (Standard) Chemical Structure

CAS No. : 945619-74-9

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Description	Ophiopogonin D (Standard) is the analytical standard of Ophiopogonin D . This product is intended for research and analytical applications. Ophiopogonin D , isolated from the tubers of Ophiopogon japonicus, is a rare naturally occurring C29 steroidal glycoside. Ophiopogonin D is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation, IκBα down-regulation, intracellular Ca2+ overload and activation of pro-inflammatory cytokines by increasing the expression of CYP2J2/EETs and PPARα in human umbilical vein endothelial cells (HUVECs). Ophiopogonin D has been used to treat inflammatory and cardiovascular diseases for thousands of years.
Molecular Weight	855.02
Formula	C₄₄H₇₀O₁₆
CAS No.	945619-74-9
SMILES	C[C@@]12[C@]([C@@H]3C)([H])[C@](O[C@]34CC[C@@H](C)CO4)([H])C[C@@]1([H])[C@@](CC=C5[C@@]6([C@@H](C[C@H](O)C5)O[C@@](O[C@H](C)[C@H](O)[C@@H]7O[C@@](OC[C@@H](O)[C@@H]8O)([H])[C@@H]8O)([H])[C@@H]7O[C@@](O[C@@H](C)[C@H](O)[C@H]9O)([H])[C@@H]9O)C)([H])[C@]6([H])CC2
Structure Classification	Steroids
Initial Source	Plants Liliaceae Ophiopogon japonicus (L. f.) Ker-Gawl.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Handling Instructions (2659 KB)

Ophiopogonin D (Standard) Related Classifications

Inflammation/Immunology Cardiovascular Disease

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ophiopogonin D (Standard)945619-74-9PPARNF-κBCalcium ChannelPeroxisome proliferator-activated receptorsNuclear factor-κBNuclear factor-kappaBCa2+ channelsCa channelsInhibitorinhibitorinhibit

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Ophiopogonin D (Standard)

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