2. GPCR/G Protein Neuronal Signaling
  3. Opioid Receptor
  4. Orphanin FQ(1-11)

Orphanin FQ(1-11), a orphanin FQ or nociceptin (OFQ/N) fragment, is a potent NOP receptor (ORL-1; OP4) agonist, with a Ki of 55 nM. Orphanin FQ(1-11) has no affinity for μ, δ, κ1 and κ3 receptors (Ki>1000 nM). Orphanin FQ(1-11) is analgesic in CD-1 mice.

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Orphanin FQ(1-11) Chemical Structure

Orphanin FQ(1-11) Chemical Structure

CAS No. : 178249-41-7

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Based on 1 publication(s) in Google Scholar

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Orphanin FQ(1-11) Related Antibodies

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μ Opioid Receptor/MOR κ Opioid Receptor/KOR δ Opioid Receptor/DOR NOP Receptor/ORL1

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Description

Orphanin FQ(1-11), a orphanin FQ or nociceptin (OFQ/N) fragment, is a potent NOP receptor (ORL-1; OP4) agonist, with a Ki of 55 nM. Orphanin FQ(1-11) has no affinity for μ, δ, κ1 and κ3 receptors (Ki>1000 nM). Orphanin FQ(1-11) is analgesic in CD-1 mice[1][2].

Molecular Weight

1098.21

Formula

C49H75N15O14
CAS No.
Appearance

Solid

Color

White to off-white

Sequence Shortening

FGGFTGARKSA
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation
References
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Orphanin FQ(1-11) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Orphanin FQ(1-11)178249-41-7Opioid ReceptornociceptionNOPreceptoraffinityanalgesicneuropeptideInhibitorinhibitorinhibit

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