1. Metabolic Enzyme/Protease
  2. Drug Metabolite
  3. Ortho-hydroxy atorvastatin lactone-d5

Ortho-hydroxy atorvastatin lactone-d5 is deuterium labeled 2-Hydroxy atorvastatin lactone. 2-Hydroxy atorvastatin lactone is a metabolite of Atorvastatin. Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids[1][2].

For research use only. We do not sell to patients.

Ortho-hydroxy atorvastatin lactone-d<sub>5</sub> Chemical Structure

Ortho-hydroxy atorvastatin lactone-d5 Chemical Structure

CAS No. : 265989-50-2

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Description

Ortho-hydroxy atorvastatin lactone-d5 is deuterium labeled 2-Hydroxy atorvastatin lactone. 2-Hydroxy atorvastatin lactone is a metabolite of Atorvastatin. Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids[1][2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

561.65

Formula

C33H28D5FN2O5

CAS No.
Unlabeled CAS

163217-74-1

SMILES

OC(C=CC=C1)=C1NC(C2=C(C(C)C)N(CC[C@@H]3C[C@H](CC(O3)=O)O)C(C4=CC=C(C=C4)F)=C2C5=C([2H])C([2H])=C([2H])C([2H])=C5[2H])=O

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
Ortho-hydroxy atorvastatin lactone-d5
Cat. No.:
HY-136346S
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