2. Immunology/Inflammation NF-κB Metabolic Enzyme/Protease Apoptosis
  3. Reactive Oxygen Species Apoptosis
  4. Osmundacetone

Osmundacetone is a natural product isolated from Osmundae Rhizoma, with neuroprotective and anti-apoptotic effects. Osmundacetone also has DPPH scavenging activity and anti-oxidative stress activity. Osmundacetone inhibits MAPK phosphorylation, including JNK, ERK, and p38 kinase. Osmundacetone can be a potential agent for the research of neurodegenerative diseases.

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Osmundacetone Chemical Structure

Osmundacetone Chemical Structure

CAS No. : 37079-84-8

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1 mg USD 70 In-stock
5 mg USD 170 In-stock
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Based on 1 publication(s) in Google Scholar

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Osmundacetone Related Antibodies

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Description

Osmundacetone is a natural product isolated from Osmundae Rhizoma, with neuroprotective and anti-apoptotic effects. Osmundacetone also has DPPH scavenging activity and anti-oxidative stress activity. Osmundacetone inhibits MAPK phosphorylation, including JNK, ERK, and p38 kinase. Osmundacetone can be a potential agent for the research of neurodegenerative diseases[1][2].

In Vitro

Osmundacetone significantly suppresses the phosphorylation of MAPKs, including JNK, ERK, and p38 kinases[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Osmundacetone Related Antibodies
Molecular Weight

178.18

Formula

C10H10O3
CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

CC(/C=C/C1=CC=C(O)C(O)=C1)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 45 mg/mL (252.55 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.6123 mL 28.0615 mL 56.1230 mL
5 mM 1.1225 mL 5.6123 mL 11.2246 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 5.6123 mL 28.0615 mL 56.1230 mL 140.3076 mL
5 mM 1.1225 mL 5.6123 mL 11.2246 mL 28.0615 mL
10 mM 0.5612 mL 2.8062 mL 5.6123 mL 14.0308 mL
15 mM 0.3742 mL 1.8708 mL 3.7415 mL 9.3538 mL
20 mM 0.2806 mL 1.4031 mL 2.8062 mL 7.0154 mL
25 mM 0.2245 mL 1.1225 mL 2.2449 mL 5.6123 mL
30 mM 0.1871 mL 0.9354 mL 1.8708 mL 4.6769 mL
40 mM 0.1403 mL 0.7015 mL 1.4031 mL 3.5077 mL
50 mM 0.1122 mL 0.5612 mL 1.1225 mL 2.8062 mL
60 mM 0.0935 mL 0.4677 mL 0.9354 mL 2.3385 mL
80 mM 0.0702 mL 0.3508 mL 0.7015 mL 1.7538 mL
100 mM 0.0561 mL 0.2806 mL 0.5612 mL 1.4031 mL
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Osmundacetone Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Osmundacetone37079-84-8Reactive Oxygen SpeciesApoptosisantioxidantDPPHscavenginganti-apoptoticneuroprotectiveneurodegenerativediseasesInhibitorinhibitorinhibit

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