1. Immunology/Inflammation NF-κB PI3K/Akt/mTOR Apoptosis
  2. COX NF-κB Akt IKK Apoptosis
  3. Oxaprozin (Standard)

Oxaprozin (Standard)  (Synonyms: Oxaprozinum (Standard); Wy21743 (Standard))

Cat. No.: HY-B0808R Purity: ≥98%
Handling Instructions

Oxaprozin (Standard) is the analytical standard of Oxaprozin. This product is intended for research and analytical applications. Oxaprozin is an orally active and potent COX inhibitor, with IC50 values of 2.2 μM for human platelet COX-1 and and 36 μM for IL-1-stimulated human synovial cell COX-2, respectively. Oxaprozin also inhibits the activation of NF-κB. Oxaprozin induces cell apoptosis. Oxaprozin shows anti-inflammatory activity. Oxaprozin-mediated inhibition of the Akt/IKK/NF-κB pathway contributes to its anti-inflammatory properties.

For research use only. We do not sell to patients.

Oxaprozin (Standard) Chemical Structure

Oxaprozin (Standard) Chemical Structure

CAS No. : 21256-18-8

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Description
Molecular Weight

293.32

Formula

C18H15NO3

CAS No.
SMILES

O=C(O)CCC1=NC(C2=CC=CC=C2)=C(C3=CC=CC=C3)O1

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Oxaprozin (Standard)
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