2. Anti-infection
  3. Bacterial Antibiotic
  4. P-113

P-113 is an antimicrobial peptide (AMP) derived from the human salivary protein histatin 5. P-113 is active against clinically important microorganisms such as Pseudomonas spp., Staphylococcus spp., and C. albicans.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

P-113 Chemical Structure

P-113 Chemical Structure

CAS No. : 190673-58-6

Size Price Stock Quantity
5 mg USD 230 In-stock
10 mg USD 350 In-stock
50 mg   Get quote  
100 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

Other Forms of P-113:

P-113 Related Antibodies

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  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

P-113 is an antimicrobial peptide (AMP) derived from the human salivary protein histatin 5. P-113 is active against clinically important microorganisms such as Pseudomonas spp., Staphylococcus spp., and C. albicans[1].

In Vitro

P-113 has a minimum inhibitory concentration (MIC) value of 3.13 μg/mL for against C. albicans[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

P-113 Related Antibodies
Molecular Weight

1563.81

Formula

C71H110N28O13
CAS No.
Appearance

Solid

Color

White to off-white

Sequence Shortening

AKRHHGYKRKFH-NH2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (63.95 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.6395 mL 3.1973 mL 6.3946 mL
5 mM 0.1279 mL 0.6395 mL 1.2789 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (63.95 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 0.6395 mL 3.1973 mL 6.3946 mL 15.9866 mL
5 mM 0.1279 mL 0.6395 mL 1.2789 mL 3.1973 mL
10 mM 0.0639 mL 0.3197 mL 0.6395 mL 1.5987 mL
15 mM 0.0426 mL 0.2132 mL 0.4263 mL 1.0658 mL
20 mM 0.0320 mL 0.1599 mL 0.3197 mL 0.7993 mL
25 mM 0.0256 mL 0.1279 mL 0.2558 mL 0.6395 mL
30 mM 0.0213 mL 0.1066 mL 0.2132 mL 0.5329 mL
40 mM 0.0160 mL 0.0799 mL 0.1599 mL 0.3997 mL
50 mM 0.0128 mL 0.0639 mL 0.1279 mL 0.3197 mL
60 mM 0.0107 mL 0.0533 mL 0.1066 mL 0.2664 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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P-113 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

P-113190673-58-6P113P 113BacterialAntibioticsalivaryproteinhistatinPseudomonasStaphylococcusC.albicansInhibitorinhibitorinhibit

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