p-Fluoro-L-phenylalanine (Synonyms: 4-Fluoro-L-phenylalanine)

Cat. No.: HY-W002291 Purity: 99.04%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

p-Fluoro-L-phenylalanine (4-Fluoro-L-phenylalanine) is a substrate for tyrosine hydroxylase (TH) that can be used to study the regulation of that enzyme. p-Fluoro-L-phenylalanine binds to the L-leucine specific receptor of Escherichia coli (K_D=0.26 μM).

For research use only. We do not sell to patients.

p-Fluoro-L-phenylalanine Chemical Structure

CAS No. : 1132-68-9

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10 g	USD 25	Ask For Quote & Lead Time
25 g	USD 57	Ask For Quote & Lead Time

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Description

Molecular Weight

183.18

Formula

C₉H₁₀FNO₂

CAS No.

1132-68-9

Appearance

Solid

Color

White to off-white

SMILES

O=C(O)[C@H](CC1=CC=C(F)C=C1)N

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

H₂O : 10 mg/mL (54.59 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.4591 mL	27.2956 mL	54.5911 mL
5 mM	1.0918 mL	5.4591 mL	10.9182 mL
10 mM	0.5459 mL	2.7296 mL	5.4591 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.91%

Select Batch:

Data Sheet (272 KB) SDS (393 KB)

COA (249 KB) HNMR (117 KB) RP-HPLC (148 KB)

Handling Instructions (2659 KB)

References

[1]. Hillas PJ, et al. A mechanism for hydroxylation by tyrosine hydroxylase based on partitioning of substituted phenylalanines. Biochemistry. 1996;35(22):6969-6975. [Content Brief]

[2]. Luck LA, et al. Fluorescence and 19F NMR evidence that phenylalanine, 3-L-fluorophenylalanine and 4-L-fluorophenylalanine bind to the L-leucine specific receptor of Escherichia coli. Protein Sci. 2000;9(12):2573-2576. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	5.4591 mL	27.2956 mL	54.5911 mL	136.4778 mL
	5 mM	1.0918 mL	5.4591 mL	10.9182 mL	27.2956 mL
	10 mM	0.5459 mL	2.7296 mL	5.4591 mL	13.6478 mL
	15 mM	0.3639 mL	1.8197 mL	3.6394 mL	9.0985 mL
	20 mM	0.2730 mL	1.3648 mL	2.7296 mL	6.8239 mL
	25 mM	0.2184 mL	1.0918 mL	2.1836 mL	5.4591 mL
	30 mM	0.1820 mL	0.9099 mL	1.8197 mL	4.5493 mL
	40 mM	0.1365 mL	0.6824 mL	1.3648 mL	3.4119 mL
	50 mM	0.1092 mL	0.5459 mL	1.0918 mL	2.7296 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

p-Fluoro-L-phenylalanine Related Classifications

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

p-Fluoro-L-phenylalanine1132-68-94-Fluoro-L-phenylalanineBiochemical Assay ReagentsInhibitorinhibitorinhibit

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