2. Membrane Transporter/Ion Channel
  3. P-glycoprotein
  4. P-gp inhibitor 19

P-gp inhibitor 19 (Compound 6i) is a P-gp inhibitor. P-gp inhibitor 19 can inhibit the efflux of rhodamine 123 (HY-D0816) in P-gp-overexpressing leukemia cells K562/Dox and also restore the sensitivity of DOX-resistant cells.

For research use only. We do not sell to patients.

P-gp inhibitor 19 Chemical Structure

P-gp inhibitor 19 Chemical Structure

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P-gp inhibitor 19 Related Antibodies

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Description

P-gp inhibitor 19 (Compound 6i) is a P-gp inhibitor. P-gp inhibitor 19 can inhibit the efflux of rhodamine 123 (HY-D0816) in P-gp-overexpressing leukemia cells K562/Dox and also restore the sensitivity of DOX-resistant cells[1].

Molecular Weight

568.87

Formula

C36H60N2O3
SMILES

[H][C@]12CC[C@]3([C@@]([C@@]1(CC[C@]4(C(C)(C)[C@H](CC[C@]24C)O)[H])C)(C)CC[C@]5(CC[C@H]([C@@]53[H])C(C)=C)COC(N6CCN(C)CC6)=O)[H]
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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P-gp inhibitor 19 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

P-gp inhibitor 19P-glycoproteinP-gpPgpMultidrug resistance protein 1MDR1ATP-binding cassette sub-family B member 1ABCB1Cluster of differentiation 243CD243LeukemiaK562/DoxDoxorubicinAntiacancerInhibitorinhibitorinhibit

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P-gp inhibitor 19
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HY-157484
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