2. Epigenetics Apoptosis
  3. DNA Methyltransferase MDM-2/p53
  4. p53 Activator 13

p53 Activator 13 (compound 11) is a 6mA methyltransferase CamA inhibitor and a p53 activator. p53 Activator 13 intercalates into CamA-bound DNA via the minor groove, causing a conformational shift that moves the catalytic domain away from the DNA and elicits DNA damage response via p53 activation. p53 Activator 13 can be utilized in cancer research.

For research use only. We do not sell to patients.

p53 Activator 13 Chemical Structure

p53 Activator 13 Chemical Structure

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p53 Activator 13 Related Antibodies

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Description

p53 Activator 13 (compound 11) is a 6mA methyltransferase CamA inhibitor and a p53 activator. p53 Activator 13 intercalates into CamA-bound DNA via the minor groove, causing a conformational shift that moves the catalytic domain away from the DNA and elicits DNA damage response via p53 activation. p53 Activator 13 can be utilized in cancer research[1].

Molecular Weight

573.69

Formula

C33H35N9O
SMILES

O=C(NC1=CC(CN2CCN(C)CC2)=CC(NC3=NC(N)=NC(C)=C3)=C1)C4=CC=CC(NC5=CC=NC6=C5C=CC=C6)=C4
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
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p53 Activator 13 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

p53 Activator 13DNA MethyltransferaseMDM-2/p53DNMTsDNA MTasesp53 Activator6mA methyltransferase CamADNA damagecancerInhibitorinhibitorinhibit

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