1. GPCR/G Protein MAPK/ERK Pathway
  2. Ras
  3. pan-KRAS-IN-15

pan-KRAS-IN-15 (compound 58) is a pan-KRAS inhibitor. pan-KRAS-IN-15 can be used in pancreatic cancer research.

For research use only. We do not sell to patients.

pan-KRAS-IN-15 Chemical Structure

pan-KRAS-IN-15 Chemical Structure

CAS No. : 3034052-52-0

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Description

pan-KRAS-IN-15 (compound 58) is a pan-KRAS inhibitor. pan-KRAS-IN-15 can be used in pancreatic cancer research[1].

IC50 & Target

K-RAS

1.4 nM (IC50)

In Vitro

pan-KRAS-IN-15 shows significant inhibitory activity on human pancreatic cancer ASPC-I cells (IC50=1.4 nM)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

642.71

Formula

C36H37F3N6O2

CAS No.
SMILES

CC#CC1=C2C(N3C[C@@H](CC4)N[C@@H]4C3)=NC(OC[C@@]56CCCN5C[C@@H](C6)F)=NC2=C(C(C7=CC(O)=CC8=C7C(CC)=C(C=C8)F)=N1)F

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
pan-KRAS-IN-15
Cat. No.:
HY-163489
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