1. PROTAC MAPK/ERK Pathway GPCR/G Protein
  2. Ligands for Target Protein for PROTAC Ras
  3. pan-KRAS ligand 1

pan-KRAS ligand 1 is a Ligand for Target Protein for PROTAC. pan-KRAS ligand 1 can be used for synthesis PROTAC pan-KRAS degrader 4 (HY-168669).

For research use only. We do not sell to patients.

pan-KRAS ligand 1 Chemical Structure

pan-KRAS ligand 1 Chemical Structure

CAS No. : 2886012-31-1

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Description

pan-KRAS ligand 1 is a Ligand for Target Protein for PROTAC. pan-KRAS ligand 1 can be used for synthesis PROTAC pan-KRAS degrader 4 (HY-168669)[1].

IC50 & Target[1]

K-RAS

 

Molecular Weight

601.60

Formula

C32H29F2N5O5

CAS No.
SMILES

O=CCOC1=NC2=C(C(C3=C4C(C#C)=C(F)C=CC4=CC(O)=C3)=NC=C2C(N5CC6N(C(CC6)C5)C(OC(C)(C)C)=O)=N1)F

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
pan-KRAS ligand 1
Cat. No.:
HY-168671
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