2. GPCR/G Protein MAPK/ERK Pathway
  3. Ras
  4. Pan-RAS-IN-3

Pan-RAS-IN-3 is a pan-Ras inhibitor, and can be used for study of melanoma and acute myeloid leukaemia.

For research use only. We do not sell to patients.

Pan-RAS-IN-3 Chemical Structure

Pan-RAS-IN-3 Chemical Structure

CAS No. : 3034588-80-9

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1 mg USD 780 In-stock
5 mg USD 1810 In-stock
10 mg USD 2900 In-stock
25 mg USD 6090 In-stock
50 mg USD 9750 In-stock
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Based on 1 publication(s) in Google Scholar

Pan-RAS-IN-3 Related Antibodies

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Description

Pan-RAS-IN-3 is a pan-Ras inhibitor, and can be used for study of melanoma and acute myeloid leukaemia[1].

Molecular Weight

712.76

Formula

C38H39F3N8O3
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

FC1=C(C2=CC(O)=CC3=C2C(CC)=C(F)C=C3)N=CC4=C1N=C(N=C4N5CC6=C7C(C(N(CC7)C)=O)=NN6CCC5)OC[C@@]89N(CCC9)C[C@@H](C8)F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (140.30 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.4030 mL 7.0150 mL 14.0300 mL
5 mM 0.2806 mL 1.4030 mL 2.8060 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.4030 mL 7.0150 mL 14.0300 mL 35.0749 mL
5 mM 0.2806 mL 1.4030 mL 2.8060 mL 7.0150 mL
10 mM 0.1403 mL 0.7015 mL 1.4030 mL 3.5075 mL
15 mM 0.0935 mL 0.4677 mL 0.9353 mL 2.3383 mL
20 mM 0.0701 mL 0.3507 mL 0.7015 mL 1.7537 mL
25 mM 0.0561 mL 0.2806 mL 0.5612 mL 1.4030 mL
30 mM 0.0468 mL 0.2338 mL 0.4677 mL 1.1692 mL
40 mM 0.0351 mL 0.1754 mL 0.3507 mL 0.8769 mL
50 mM 0.0281 mL 0.1403 mL 0.2806 mL 0.7015 mL
60 mM 0.0234 mL 0.1169 mL 0.2338 mL 0.5846 mL
80 mM 0.0175 mL 0.0877 mL 0.1754 mL 0.4384 mL
100 mM 0.0140 mL 0.0701 mL 0.1403 mL 0.3507 mL
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Pan-RAS-IN-3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pan-RAS-IN-33034588-80-9Rasmelanomaacute myeloid leukaemiaInhibitorinhibitorinhibit

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