2. NF-κB
  3. NF-κB
  4. PapRIV

PapRIV is an agonist of BV-2 microglial cells, capable of activating microglial cells through an NF-κB-dependent pathway. PapRIV induces the expression of pro-inflammatory cytokines such as IL-6 and TNFα and increases the production of reactive oxygen species (ROS). PapRIV can cross the blood-brain barrier.

For research use only. We do not sell to patients.

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PapRIV Chemical Structure

PapRIV Chemical Structure

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PapRIV Related Antibodies

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Description

PapRIV is an agonist of BV-2 microglial cells, capable of activating microglial cells through an NF-κB-dependent pathway. PapRIV induces the expression of pro-inflammatory cytokines such as IL-6 and TNFα and increases the production of reactive oxygen species (ROS). PapRIV can cross the blood-brain barrier[1].

Molecular Weight

843.88

Formula

C38H53N9O13
Sequence

Ser-Asp-Leu-Pro-Phe-Glu-His
Sequence Shortening

SDLPFEH
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PapRIV Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PapRIVNF-κBNuclear factor-κBNuclear factor-kappaBNF-κB pathwayPro-inflammatory cytokine inducerReactive oxygen species (ROS) inducerInhibitorinhibitorinhibit

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