1. PI3K/Akt/mTOR MAPK/ERK Pathway Membrane Transporter/Ion Channel Epigenetics Cell Cycle/DNA Damage Autophagy Apoptosis
  2. Akt p38 MAPK P-glycoprotein Bcl-2 Family Caspase PARP Autophagy Apoptosis
  3. Paris saponin VII (Standard)

Paris saponin VII (Standard) 

Cat. No.: HY-N3584R Purity: ≥98%
Handling Instructions

Paris saponin VII (Standard) is the analytical standard of Paris saponin VII. This product is intended for research and analytical applications. Paris saponin VII (Chonglou Saponin VII) is a steroidal saponin isolated from the roots and rhizomes of Trillium tschonoskii. Paris saponin VII-induced apoptosis in K562/ADR cells is associated with Akt/MAPK and the inhibition of P-gp. Paris saponin VII attenuates mitochondrial membrane potential, increases the expression of apoptosis-related proteins, such as Bax and cytochrome c, and decreases the protein expression levels of Bcl-2, caspase-9, caspase-3, PARP-1, and p-Akt. Paris saponin VII induces a robust autophagy in K562/ADR cells and provides a biochemical basis in the treatment of leukemia.

For research use only. We do not sell to patients.

Paris saponin VII (Standard) Chemical Structure

Paris saponin VII (Standard) Chemical Structure

CAS No. : 68124-04-9

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Description
Molecular Weight

1031.18

Formula

C51H82O21

CAS No.
SMILES

O[C@@]12[C@@]3([C@@]([C@@]4([H])[C@]([C@@]5(C(C[C@@H](O[C@@]6([H])[C@@H]([C@H]([C@H](O[C@@]7([H])[C@@H]([C@@H]([C@@H](O[C@@]8([H])[C@@H]([C@@H]([C@@H](O)[C@H](C)O8)O)O)[C@H](C)O7)O)O)[C@@H](CO)O6)O)O[C@@]9([H])[C@@H]([C@@H]([C@@H](O)[C@H](C)O9)O)O)CC5)=CC4)C)([H])CC3)([H])C[C@]1([H])O[C@]%10(CC[C@@H](C)CO%10)[C@H]2C)C

Structure Classification
Initial Source
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Paris saponin VII (Standard)
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