Parogrelil hydrochloride (Synonyms: NM-702; NT-702)

Cat. No.: HY-111219: FAQs
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Parogrelil (hydrochloride) (NM-702) is a phosphodiesterase inhibitor with activity in inhibiting intermittent claudication. Parogrelil (hydrochloride) selectively inhibits PDE3, inhibits human platelet aggregation in vitro and rat aortic contraction, and improves walking distance and plantar surface temperature in the rat femoral artery ligation model, with better effects than cilostazol.

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Parogrelil hydrochloride Chemical Structure

CAS No. : 139145-84-9

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Other Forms of Parogrelil hydrochloride:

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Description	Parogrelil (hydrochloride) (NM-702) is a phosphodiesterase inhibitor with activity in inhibiting intermittent claudication. Parogrelil (hydrochloride) selectively inhibits PDE3, inhibits human platelet aggregation in vitro and rat aortic contraction, and improves walking distance and plantar surface temperature in the rat femoral artery ligation model, with better effects than cilostazol.
Molecular Weight	486.19
Formula	C₁₉H₁₉BrCl₂N₄O₂
CAS No.	139145-84-9
SMILES	O=C1C(Br)=C(NCC2=CC=CN=C2)C(OCCCC3=CC=C(Cl)C=C3)=NN1.Cl
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (267 KB) Handling Instructions (2659 KB)
References	[1]. NT-702 (parogrelil hydrochloride, NM-702), a novel and potent phosphodiesterase inhibitor, improves reduced walking distance and lowered hindlimb plantar surface temperature in a rat experimental intermittent claudication model

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Parogrelil139145-84-9NM-702 NT-702NM702NM 702NT702NT 702NT-702OthersInhibitorinhibitorinhibit

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Parogrelil hydrochloride (Synonyms: NM-702; NT-702)

Other Forms of Parogrelil hydrochloride:

Parogrelil hydrochloride Related Antibodies

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Biological Activity

Purity & Documentation

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