2. Cell Cycle/DNA Damage Epigenetics
  3. PARP
  4. PARP-1/2/7-IN-1

PARP-1/2/7-IN-1 (compound 86) is a potent inhibitor of PARP-1/2/7, with the IC50 of ＜ 10 nM.

For research use only. We do not sell to patients.

PARP-1/2/7-IN-1 Chemical Structure

PARP-1/2/7-IN-1 Chemical Structure

CAS No. : 3034665-49-8

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PARP-1/2/7-IN-1 Related Antibodies

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PARP PARP1 PARP2 PARP3 PARP4 TNKS1/PARP5A TNKS2/PARP5B PARP7 PARP10 PARP14 PARP15 PARP12 PARP16

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Description

PARP-1/2/7-IN-1 (compound 86) is a potent inhibitor of PARP-1/2/7, with the IC50 of ＜ 10 nM[1].

IC50 & Target

PARP1

 

PARP2

 

PARP7

 

Molecular Weight

547.45

Formula

C22H23F6N7O3
CAS No.
SMILES

O=C1NN=C2C(CC[C@H]2N3C[C@H](C(N4CCN(C5=NC=C(C(F)(F)F)C=N5)CC4)=O)OCC3)=C1C(F)(F)F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PARP-1/2/7-IN-1 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PARP-1/2/7-IN-13034665-49-8PARPpoly ADP ribose polymeraseCpd AOlaparibInhibitorinhibitorinhibit

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