2. Epigenetics
  3. Epigenetic Reader Domain
  4. PBRM1-BD2-IN-4

PBRM1-BD2-IN-4 (compound 15) is a potent PBRM1 Bromodomain inhibitor with Kd values of 5.5 μM and 11.1 μM for PBRM1-BD2 and PBRM1-BD5, respectively, and an IC50 value of 0.2 μM for PBRM1-BD2. PBRM1-BD2-IN-4 can be used to research anticancer.

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PBRM1-BD2-IN-4 Chemical Structure

PBRM1-BD2-IN-4 Chemical Structure

CAS No. : 2819989-60-9

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PBRM1-BD2-IN-4 Related Antibodies

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Description

PBRM1-BD2-IN-4 (compound 15) is a potent PBRM1 Bromodomain inhibitor with Kd values of 5.5 μM and 11.1 μM for PBRM1-BD2 and PBRM1-BD5, respectively, and an IC50 value of 0.2 μM for PBRM1-BD2. PBRM1-BD2-IN-4 can be used to research anticancer[1].

IC50 & Target

Kd: 5.5 μM (PBRM1-BD2), 11.1 μM (PBRM1-BD5)[1]
IC50: 0.2 μM (PBRM1-BD2)[1]
Molecular Weight

272.73

Formula

C15H13ClN2O
CAS No.
SMILES

O=C1NC(C2=CC=CC=C2C)NC3=C1C(Cl)=CC=C3
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Purity & Documentation
References
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PBRM1-BD2-IN-4 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PBRM1-BD2-IN-42819989-60-9Epigenetic Reader DomainanticancerPBRM1BD2BD5Inhibitorinhibitorinhibit

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