2. Metabolic Enzyme/Protease
  3. LDLR PCSK9
  4. PCSK9-IN-29

PCSK9-IN-29 is a lipid-lowering agent. PCSK9-IN-29 can increase low-density lipoprotein receptor (LDLR) protein expression and decrease PCSK9 protein expression in hepG2 cells. PCSK9-IN-29 can reduce the levels of serum LDL-C, TC, and liver enzyme ALT in crab eating macaques fed a high-fat diet, lower body weight and fat, and increase bone mineral content. PCSK9-IN-29 can be used for research on non-alcoholic fatty liver disease and obesity.

For research use only. We do not sell to patients.

PCSK9-IN-29 Chemical Structure

PCSK9-IN-29 Chemical Structure

CAS No. : 1233353-86-0

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PCSK9-IN-29 Related Antibodies

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Description

PCSK9-IN-29 is a lipid-lowering agent. PCSK9-IN-29 can increase low-density lipoprotein receptor (LDLR) protein expression and decrease PCSK9 protein expression in hepG2 cells. PCSK9-IN-29 can reduce the levels of serum LDL-C, TC, and liver enzyme ALT in crab eating macaques fed a high-fat diet, lower body weight and fat, and increase bone mineral content. PCSK9-IN-29 can be used for research on non-alcoholic fatty liver disease and obesity[1].
Molecular Weight

499.55

Formula

C26H26FNO6S
CAS No.
SMILES

O=S(OC1=C(CN2CCC3=CC(OC)=C(C=C3C2C4)OC)C4=CC=C1OC)(C5=CC(F)=CC=C5)=O
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PCSK9-IN-29 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PCSK9-IN-291233353-86-0LDLRPCSK9Low-density lipoprotein receptorProprotein convertase subtilisin/kexin type 9LDL-CALTnonalcoholic steatohepatitisobesityInhibitorinhibitorinhibit

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