2. Metabolic Enzyme/Protease
  3. Phosphodiesterase (PDE)
  4. PDE4B/D-IN-4

PDE4B/D-IN-4 (compound 4p) is a potent inhibitor of PDE-4B and PDE-4D, with IC50s of 5.50 nM and 6.81 nM, respectively. PDE4B/D-IN-4 shows an increase in the level of intracellular cAMP.

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PDE4B/D-IN-4 Chemical Structure

PDE4B/D-IN-4 Chemical Structure

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PDE4B/D-IN-4 Related Antibodies

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Description

PDE4B/D-IN-4 (compound 4p) is a potent inhibitor of PDE-4B and PDE-4D, with IC50s of 5.50 nM and 6.81 nM, respectively. PDE4B/D-IN-4 shows an increase in the level of intracellular cAMP[1].

IC50 & Target[1]

PDE4B

5.50 nM (IC50)

PDE4D

6.81 nM (IC50)

Molecular Weight

406.38

Formula

C20H20F2N2O5
SMILES

O=C(N/N=C/C1=CC=C(OC)C(O)=C1)C2=CC=C(OC(F)F)C(OCC3CC3)=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PDE4B/D-IN-4 Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PDE4B/D-IN-4Phosphodiesterase (PDE)roflumilastcAMPInhibitorinhibitorinhibit

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