2. Metabolic Enzyme/Protease
  3. Phosphodiesterase (PDE)
  4. PDE5-IN-42

PDE5-IN-42 (Compound 42) is a potent and orally active PDE5 inhibitor with an IC50 of 0.04 nM. PDE5-IN-42 maintains selectivity over PDE6 and PDE11.

For research use only. We do not sell to patients.

PDE5-IN-42 Chemical Structure

PDE5-IN-42 Chemical Structure

CAS No. : 936449-28-4

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PDE5-IN-42 Related Antibodies

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PDE1 PDE2 PDE3 PDE4 PDE5 PDE6 PDE7 PDE9 PDE10 PDE11 PDE12 PDE8 Autotaxin

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Description

PDE5-IN-42 (Compound 42) is a potent and orally active PDE5 inhibitor with an IC50 of 0.04 nM. PDE5-IN-42 maintains selectivity over PDE6 and PDE11[1].

IC50 & Target

IC50: 0.04 nM (PDE5)[1]
Molecular Weight

453.54

Formula

C23H31N7O3
CAS No.
SMILES

O=C(C1CCN(C2=NC(NC3=NC=CC(C)=C3)=C(N(CCOCC)N=C4CC)C4=N2)CC1)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PDE5-IN-42 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PDE5-IN-42936449-28-4Phosphodiesterase (PDE)hypertensive ratslow clearanceInhibitorinhibitorinhibit

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