1. Metabolic Enzyme/Protease
  2. Phosphodiesterase (PDE)
  3. PDE5-IN-5

PDE5-IN-5 (Compound 11) is a potent, selective phosphodiesterase 5 (PDE5) inhibitor with an IC50 of 2.0 nM.

For research use only. We do not sell to patients.

PDE5-IN-5 Chemical Structure

PDE5-IN-5 Chemical Structure

CAS No. : 2414921-33-6

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Description

PDE5-IN-5 (Compound 11) is a potent, selective phosphodiesterase 5 (PDE5) inhibitor with an IC50 of 2.0 nM[1].

IC50 & Target

PDE5

2.0 nM (IC50)

Molecular Weight

482.33

Formula

C23H20BrN3O4

CAS No.
SMILES

O=C(O)CCN(C1)C([C@@]2([H])CC3=C([C@@H](C4=CC=C(Br)C=C4)N2C1=O)NC5=C3C=CC=C5)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
PDE5-IN-5
Cat. No.:
HY-147990
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