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PDHK-IN-7 (compound 32) is an inhibitor of pyruvate dehydrogenase kinase with an IC50 value of 17 nM.PDHK-IN-7 activates PDH in rat livers and has a glucose-lowering effect in Zucker fatty rats.

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PDHK-IN-7 Chemical Structure

PDHK-IN-7 Chemical Structure

CAS No. : 1220965-73-0

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PDHK-IN-7 Related Antibodies

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Description

PDHK-IN-7 (compound 32) is an inhibitor of pyruvate dehydrogenase kinase with an IC50 value of 17 nM.PDHK-IN-7 activates PDH in rat livers and has a glucose-lowering effect in Zucker fatty rats[1].

Molecular Weight

374.36

Formula

C20H17F3N2O2
CAS No.
SMILES

CC1=CC2=C(C3=CC=CC=C3C2(O)C(F)(F)F)C(C4=CN(CCO)N=C4)=C1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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PDHK-IN-7 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PDHK-IN-71220965-73-0Otherspyruvate dehydrogenase kinasepyruvate dehydrogenase glucose-loweringInhibitorinhibitorinhibit

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HY-162586
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