2. PI3K/Akt/mTOR
  3. Akt
  4. PDK1/Akt/Flt dual pathway inhibitor

PDK1/Akt/Flt dual pathway inhibitor is one of a component of KP372-1 (HY-15673 ), and inhibits PDK1/Akt/Flt dual pathway.

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PDK1/Akt/Flt dual pathway inhibitor Chemical Structure

PDK1/Akt/Flt dual pathway inhibitor Chemical Structure

CAS No. : 331253-86-2

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PDK1/Akt/Flt dual pathway inhibitor Related Antibodies

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Description

PDK1/Akt/Flt dual pathway inhibitor is one of a component of KP372-1 (HY-15673 ), and inhibits PDK1/Akt/Flt dual pathway[1].

Molecular Weight

224.18

Formula

C10H4N6O
CAS No.
SMILES

O=C1C2=C(C3=NC4=NN=NN4N=C31)C=CC=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro: 

DMSO : 20 mg/mL (89.21 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.4607 mL 22.3035 mL 44.6070 mL
5 mM 0.8921 mL 4.4607 mL 8.9214 mL
View the Complete Stock Solution Preparation Table

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.4607 mL 22.3035 mL 44.6070 mL 111.5175 mL
5 mM 0.8921 mL 4.4607 mL 8.9214 mL 22.3035 mL
10 mM 0.4461 mL 2.2304 mL 4.4607 mL 11.1518 mL
15 mM 0.2974 mL 1.4869 mL 2.9738 mL 7.4345 mL
20 mM 0.2230 mL 1.1152 mL 2.2304 mL 5.5759 mL
25 mM 0.1784 mL 0.8921 mL 1.7843 mL 4.4607 mL
30 mM 0.1487 mL 0.7435 mL 1.4869 mL 3.7173 mL
40 mM 0.1115 mL 0.5576 mL 1.1152 mL 2.7879 mL
50 mM 0.0892 mL 0.4461 mL 0.8921 mL 2.2304 mL
60 mM 0.0743 mL 0.3717 mL 0.7435 mL 1.8586 mL
80 mM 0.0558 mL 0.2788 mL 0.5576 mL 1.3940 mL
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PDK1/Akt/Flt dual pathway inhibitor Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PDK1/Akt/Flt dual pathway inhibitor331253-86-2AktPKBProtein kinase BPDK1/Akt/Flt pathwaycancerInhibitorinhibitorinhibit

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PDK1/Akt/Flt dual pathway inhibitor
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