Pentosidine

Cat. No.: HY-113033: FAQs
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Pentosidine is an advanced glycation end product (AGE) and cross-linked substance with fluorescent properties. Pentosidine is present in various human tissues and can serve as a biomarker for diabetes, aging, uremia, protein accumulation damage, and non-enzymatic modification of long-lived proteins in the Maillard reaction. It aids in gaining a deeper understanding of the overall role of the Maillard reaction in aging and disease.

For research use only. We do not sell to patients.

Pentosidine Chemical Structure

CAS No. : 124505-87-9

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Description	Pentosidine is an advanced glycation end product (AGE) and cross-linked substance with fluorescent properties. Pentosidine is present in various human tissues and can serve as a biomarker for diabetes, aging, uremia, protein accumulation damage, and non-enzymatic modification of long-lived proteins in the Maillard reaction. It aids in gaining a deeper understanding of the overall role of the Maillard reaction in aging and disease^[1]^[2].
Molecular Weight	378.43
Formula	C₁₇H₂₆N₆O₄
CAS No.	124505-87-9
SMILES	OC([C@@H](N)CCCCN1C2=NC(NCCC[C@H](N)C(O)=O)=NC2=CC=C1)=O
Structure Classification	Others
Initial Source	Endogenous metabolite Disease markers
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (271 KB) Handling Instructions (2659 KB)
References	[1]. Sell DR, et al. Pentosidine: a molecular marker for the cumulative damage to proteins in diabetes, aging, and uremia. Diabetes Metab Rev. 1991;7(4):239-251. [Content Brief] [2]. Requena JR, et al. Measurement of pentosidine in biological samples. Methods Mol Med. 2000;38:209-17. [Content Brief]

Pentosidine Related Classifications

Neurological Disease Metabolic Disease

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pentosidine124505-87-9OthersMaillard reactionagingdiabetesuremiaInhibitorinhibitorinhibit

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Pentosidine

Other Forms of Pentosidine:

Pentosidine Related Antibodies

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity

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