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  4. PF-05387252

PF-05387252 is a potent and selective IRAK4 inhibitor with the activity of inhibiting endogenous TLR signaling pathways. PF-05387252 has shown anti-inflammatory activity in experimental models and may have potential clinical application value in inhibiting psoriasis. Although PF-05387252 and its related compounds have shown anti-inflammatory effects in animal models, their efficacy in inhibiting psoriasis has not yet been verified.

For research use only. We do not sell to patients.

PF-05387252 Chemical Structure

PF-05387252 Chemical Structure

CAS No. : 1604034-71-0

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PF-05387252 Related Antibodies

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Description

PF-05387252 is a potent and selective IRAK4 inhibitor with the activity of inhibiting endogenous TLR signaling pathways. PF-05387252 has shown anti-inflammatory activity in experimental models and may have potential clinical application value in inhibiting psoriasis. Although PF-05387252 and its related compounds have shown anti-inflammatory effects in animal models, their efficacy in inhibiting psoriasis has not yet been verified[1].

Molecular Weight

429.51

Formula

C25H27N5O2
CAS No.
SMILES

N#CC1=CC2=C(C=C1)C3=C(C4=CC(OC)=C(C=C4N=C3)OCCCN5CCN(CC5)C)N2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PF-05387252 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PF-053872521604034-71-0PF05387252PF 05387252OthersInhibitorinhibitorinhibit

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