2. Cytoskeleton
  3. Arp2/3 Complex
  4. Phallacidin

Phallacidin is a member of the phallotoxin family of mushroom toxins. Phallacidin binds F-actin.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Phallacidin Chemical Structure

Phallacidin Chemical Structure

CAS No. : 26645-35-2

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Based on 1 publication(s) in Google Scholar

Phallacidin Related Antibodies

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  • Biological Activity

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Description

Phallacidin is a member of the phallotoxin family of mushroom toxins. Phallacidin binds F-actin[1].

Molecular Weight

846.90

Formula

C37H50N8O13S
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Ala-Trp-Leu-Val-{D-Asp}-Cys-{Hyp} (Sulfide bridge: Trp2- Cys6)
Sequence Shortening

AWLV-{D-Asp}-C-{Hyp} (Sulfide bridge: Trp2- Cys6)
Structure Classification
Initial Source

Amanita exitialis basidiocarps
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O

Peptide Solubility and Storage Guidelines:

1.  Calculate the length of the peptide.

2.  Calculate the overall charge of the entire peptide according to the following table:

  Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.  Recommended solution:

Overall charge of peptide Details
Negative (<0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, add NH4OH (<50 μL).
3.  If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.  If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.  Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.  For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
Purity & Documentation

Purity: 92.4%

COA (257 KB)

Handling Instructions (2659 KB)
References
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Phallacidin Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Phallacidin26645-35-2Arp2/3 ComplexActin-related protein 2/3 complexInhibitorinhibitorinhibit

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Phallacidin
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HY-P2031
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