Phenaglycodol

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Phenaglycodol belongs to the group of butanediolsa with anxiolytic and anticonvulsant porperties. Phenaglycodol has orally bioactivity.

For research use only. We do not sell to patients.

Phenaglycodol Chemical Structure

CAS No. : 79-93-6

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1 mg	USD 95	Ask For Quote & Lead Time
5 mg	USD 200	Ask For Quote & Lead Time
10 mg	USD 325	Ask For Quote & Lead Time

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Description

Phenaglycodol belongs to the group of butanediolsa with anxiolytic and anticonvulsant porperties. Phenaglycodol has orally bioactivity^[1].

In Vivo

Phenaglycodol (20 mg/kg, i.p.,1 time ) has antiepileptic activity in cat^[1].
Phenaglycodol (55-80 mg/kg, i.p., 1 time) has antiepileptic activity in mice^[1].
Phenaglycodol (50-100 mg/kg, i.g., 1 time) has antiepileptic activity in monkey^[1].
Phenaglycodol (130mg/kg, i.p., 1 time) lowers the concentration of Meprobamate in serum and brain^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Cat^[1]
Dosage:	20 mg/kg
Administration:	Intraperitoneal Injection (i.p.)
Result:	Showed that cat became quiet.

Animal Model:	Monkey^[1]
Dosage:	50-100 mg/kg
Administration:	Intragastric Gavage (i.g.)
Result:	Showed that monkey became less aggressive or less fearful.

Animal Model:	Mice^[1]
Dosage:	55-80 mg/kg
Administration:	Intraperitoneal Injection (i.p.)
Result:	Showed a reduction in spontaneous activity and sit quietly.

Animal Model:	Female Rats(Sprague-Dawley, 170g)^[2]
Dosage:	130 mg/kg
Administration:	Intraperitoneal Injection (i.p.)
Result:	Showed that the decrease of Meprobamate concentration in the serum and brain of the pretrealed rats was more rapid than that in control rats.

Molecular Weight

214.69

Formula

C₁₁H₁₅ClO₂

CAS No.

79-93-6

SMILES

ClC1=CC=C(C(C)(C(C)(C)O)O)C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. G T JONES, et al. Mode of action of phenaglycodol, a new neurosedative agent. Proc Soc Exp Biol Med. 1956 Dec;93(3):528-31. [Content Brief]

[2]. R. KATO, et al. Induced Increase o f M eprobam ate M etabolism in R ats T reated w ith P hénobarbital or Phenaglycodol. Pharmacology (1970) 3 (2): 95–100. [Content Brief]

Phenaglycodol Related Classifications

Neurological Disease

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Phenaglycodol79-93-6OthersInhibitorinhibitorinhibit

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