2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. iGluR
  4. Philanthotoxin 74 diTFA

Philanthotoxin 74 diTFA  (Synonyms: PhTx 74 diTFA)

Cat. No.: HY-104020B
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Philanthotoxin 74 (PhTx 74) diTFA is an AMPAR antagonist; inhibits GluR3 and GluR1 with IC50s of 263 and 296 nM, respectively.

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Philanthotoxin 74 diTFA Chemical Structure

Philanthotoxin 74 diTFA Chemical Structure

CAS No. : 401601-12-5

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Philanthotoxin 74 diTFA Related Antibodies

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Description

Philanthotoxin 74 (PhTx 74) diTFA is an AMPAR antagonist; inhibits GluR3 and GluR1 with IC50s of 263 and 296 nM, respectively[1][2].

IC50 & Target

IC50: 296 nM (GluR1), 293 nM (GluR3)[1] Ki: 0.29 μM (GluR5Q)[2]
Molecular Weight

662.66

Formula

C28H44F6N4O7
CAS No.
SMILES

O=C(NCCCCCCCNCCCCN)[C@@H](NC(CCC)=O)CC1=CC=C(O)C=C1.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Philanthotoxin 74 diTFA Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Philanthotoxin 74 diTFA401601-12-5PhTx 74 diTFAiGluRIonotropic glutamate receptorsInhibitorinhibitorinhibit

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