2. PI3K/Akt/mTOR
  3. PI3K
  4. PI3Kδ-IN-9

PI3Kδ-IN-9 is a selective PI3Kδ inhibitor with an IC50 value of 3.8 nM.

For research use only. We do not sell to patients.

PI3Kδ-IN-9 Chemical Structure

PI3Kδ-IN-9 Chemical Structure

CAS No. : 2135922-40-4

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PI3Kδ-IN-9 Related Antibodies

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PI3Kα PI3Kβ PI3Kγ PI3Kδ PI3KC2α PI3KC2β PI3KC2γ Vps34 PI3K PI3KC3 p120γ

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Description

PI3Kδ-IN-9 is a selective PI3Kδ inhibitor with an IC50 value of 3.8 nM.

Cellular Effect
Cell Line Type Value Description References
HeLa IC50
5.4 μM
Compound: 4d; L-006021422
Inhibition of [3H]adenosine uptake in human HeLa cells preincubated for 30 mins followed by incubation with [3H]adenosine for 60 mins by TopCount plate reader analysis
Inhibition of [3H]adenosine uptake in human HeLa cells preincubated for 30 mins followed by incubation with [3H]adenosine for 60 mins by TopCount plate reader analysis
[PMID: 33335668]
Molecular Weight

475.52

Formula

C24H26FN9O
CAS No.
SMILES

O=C1[C@@](C)(NCC(C)(F)C)C2=CC(C3=C4N=C(C5=CN=C(C)N=C5)N(CC)C4=NC=N3)=CN=C2N1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PI3Kδ-IN-9 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PI3Kδ-IN-92135922-40-4PI3KPhosphoinositide 3-kinaseInhibitorinhibitorinhibit

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