2. PI3K/Akt/mTOR Apoptosis Autophagy
  3. PI4K Apoptosis Autophagy PI3K Akt
  4. PI4KIII beta inhibitor 4

PI4KIII beta inhibitor 4 (Compound 16) is a selective PI4KIIIβ inhibitor with an IC50 of 0.005 μM. PI4KIIIβ inhibitor 4 induces tumor cell apoptosis, cell cycle arrest, and autophagy by inhibiting the PI3K/AKT pathway. PI4KIIIβ inhibitor 4 can be used in the study of cancer.

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PI4KIII beta inhibitor 4 Chemical Structure

PI4KIII beta inhibitor 4 Chemical Structure

CAS No. : 3029505-94-7

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PI4KIII beta inhibitor 4 Related Antibodies

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PI4KIIIβ PI4KIIIα PI4K PI4KII

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PI3Kα PI3Kβ PI3Kγ PI3Kδ PI3KC2α PI3KC2β PI3KC2γ Vps34 PI3K PI3KC3 p120γ

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Description

PI4KIII beta inhibitor 4 (Compound 16) is a selective PI4KIIIβ inhibitor with an IC50 of 0.005 μM. PI4KIIIβ inhibitor 4 induces tumor cell apoptosis, cell cycle arrest, and autophagy by inhibiting the PI3K/AKT pathway. PI4KIIIβ inhibitor 4 can be used in the study of cancer[1].

IC50 & Target[1]

PI4KIIIβ

0.005 μM (IC50)

Molecular Weight

540.70

Formula

C24H36N4O6S2
CAS No.
SMILES

O=S(C1=C(C=CC(C2=C(N=C(S2)NC(CCCCC)=O)C)=C1)OC)(NCCNC(OC(C)(C)C)=O)=O
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Purity & Documentation
References
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PI4KIII beta inhibitor 4 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PI4KIII beta inhibitor 43029505-94-7PI4KApoptosisAutophagyPI3KAktPhosphatidylinositol 4 kinasesPI4 kinasesPhosphoinositide 3-kinasePKBProtein kinase BMCF-7MDA-MB-231A549H446DU145PC3HT29HCT116H1975H1650H2228PC9Huh-7Lung cancer modelInhibitorinhibitorinhibit

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