Picrotoxinin (Standard)

Cat. No.: HY-B1494R Purity: ≥98%: FAQs
Handling Instructions

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Picrotoxinin (Standard) is the analytical standard of Picrotoxinin. This product is intended for research and analytical applications. Picrotoxinin, a potent convulsant, is a chloride channel blocker. Picrotoxinin is a noncompetitive GABAA receptor antagonist, which negatively modulates the action of GABA on GABAA receptors. Picrotoxinin inhibits α1β2γ2L GABAA receptor with an IC₅₀ of 1.15 μM.

For research use only. We do not sell to patients.

Picrotoxinin (Standard) Chemical Structure

CAS No. : 17617-45-7

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Description	Picrotoxinin (Standard) is the analytical standard of Picrotoxinin . This product is intended for research and analytical applications. Picrotoxinin , a potent convulsant, is a chloride channel blocker. Picrotoxinin is a noncompetitive GABAA receptor antagonist, which negatively modulates the action of GABA on GABAA receptors. Picrotoxinin inhibits α1β2γ2L GABAA receptor with an IC₅₀ of 1.15 μM.
Molecular Weight	292.28
Formula	C₁₅H₁₆O₆
CAS No.	17617-45-7
SMILES	O=C1[C@]([C@@H]2C(C)=C)([H])[C@]3(O)C[C@]4([H])[C@](O4)(C(O5)=O)[C@]3(C)[C@@]5([H])[C@]2([H])O1
Structure Classification	Others
Initial Source	Plants other families
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Handling Instructions (2659 KB)

Picrotoxinin (Standard) Related Classifications

Neurological Disease

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Picrotoxinin (Standard)17617-45-7Chloride ChannelGABA ReceptorCl− Channels Gamma-aminobutyric acid Receptorγ-Aminobutyric acid ReceptorGABAAGABAreceptorvoltageclampchlorideInhibitorinhibitorinhibit

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