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  3. PIN1 inhibitor 2

PIN1 inhibitor 2 (compound 12) is a potent PIN1 inhibitor. PIN1 inhibitor 2 shows antitumor activity with an IC50 of 9.55 µM for MCF7 cells. PIN1 inhibitor 2 has the potential for the research of breast cancer.

For research use only. We do not sell to patients.

PIN1 inhibitor 2 Chemical Structure

PIN1 inhibitor 2 Chemical Structure

CAS No. : 2417101-28-9

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Description

PIN1 inhibitor 2 (compound 12) is a potent PIN1 inhibitor. PIN1 inhibitor 2 shows antitumor activity with an IC50 of 9.55 µM for MCF7 cells. PIN1 inhibitor 2 has the potential for the research of breast cancer[1].

IC50 & Target

PIN1[1]

Cellular Effect
Cell Line Type Value Description References
MCF7 IC50
9.55 μM
Compound: 12
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 24 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 24 hrs by MTT assay
[PMID: 32307260]
Molecular Weight

319.49

Formula

C16H21N3S2

CAS No.
SMILES

CC1=C(C=C2NC(CSC(N3CCCCC3)=S)=NC2=C1)C

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Room temperature in continental US; may vary elsewhere.

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Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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PIN1 inhibitor 2
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HY-147710
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