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  6. Platyphyllenone

Platyphyllenone is a narutal product that can be isolated from Alnus japonica.

For research use only. We do not sell to patients.

Platyphyllenone Chemical Structure

Platyphyllenone Chemical Structure

CAS No. : 56973-65-0

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Platyphyllenone Related Antibodies

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Description

Platyphyllenone is a narutal product that can be isolated from Alnus japonica[1].

Cellular Effect
Cell Line Type Value Description References
HEK293 EC50
45 μM
Compound: 46
Cytotoxicity against HEK293 cells after 16 hrs by alamar blue assay
Cytotoxicity against HEK293 cells after 16 hrs by alamar blue assay
[PMID: 20004045]
HSC-T6 IC50
34.7 μM
Compound: 1
Antifibrotic activity against rat HSC-T6 cells assessed as inhibition of proliferation after 48 hrs by BrdU incorporation assay
Antifibrotic activity against rat HSC-T6 cells assessed as inhibition of proliferation after 48 hrs by BrdU incorporation assay
[PMID: 21504848]
RAW264.7 IC50
15.9 μM
Compound: 35
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production preincubated for 1 hrs followed by LPS stimulation and measured after 24 hrs by Griess reagent based analysis
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production preincubated for 1 hrs followed by LPS stimulation and measured after 24 hrs by Griess reagent based analysis
[PMID: 33422907]
RAW264.7 IC50
30.7 μM
Compound: 35
Cytotoxicity against mouse RAW264.7 cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against mouse RAW264.7 cells assessed as reduction in cell viability by MTT assay
[PMID: 33422907]
RAW264.7 IC50
6.9 μM
Compound: 35
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production preincubated for 0.5 hrs followed by LPS stimulation and measured after 24 hrs by Griess reagent based analysis
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production preincubated for 0.5 hrs followed by LPS stimulation and measured after 24 hrs by Griess reagent based analysis
[PMID: 33422907]
Molecular Weight

296.36

Formula

C19H20O3
CAS No.
SMILES

OC(C=C1)=CC=C1CC/C=C/C(CCC2=CC=C(O)C=C2)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Platyphyllenone Related Classifications

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The molarity calculator equation

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Platyphyllenone56973-65-0OthersNatural ProductsAlnus japonicaInhibitorinhibitorinhibit

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