2. Cell Cycle/DNA Damage
  3. Polo-like Kinase (PLK)
  4. PLK1-IN-8

PLK1-IN-8 (compound TE6) is a PLK1 inhibitor, and inhibits cell proliferation by blocking the cell cycle at G2 phase. PLK1-IN-8 shows anticancer activity in vivo.

For research use only. We do not sell to patients.

PLK1-IN-8 Chemical Structure

PLK1-IN-8 Chemical Structure

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PLK1-IN-8 Related Antibodies

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Description

PLK1-IN-8 (compound TE6) is a PLK1 inhibitor, and inhibits cell proliferation by blocking the cell cycle at G2 phase. PLK1-IN-8 shows anticancer activity in vivo[1].

Molecular Weight

447.42

Formula

C22H13N3O6S
SMILES

O=C(C1=CC=CC=C1C2=C3C(C)=C(CSC4=NN=C(C5=CC=C([N+]([O-])=O)C=C5)O4)O2)C3=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PLK1-IN-8 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PLK1-IN-8Polo-like Kinase (PLK)Cell cycleInhibitorL-shaped ortho-quinone analogPLK1Prostate cancerinhibitorinhibit

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HY-161046
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