1. Peptides
  2. Peptide and Derivatives
  3. Inhibitors and Substrates
  4. Ion Channel Modulators
  5. PLTX-II

PLTX-II is a calcium channel blocker. PLTX-II has a 44-residue peptide containing ten Cys residues and an O-palmitoylated threonine amide at the carboxy-terminus.

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PLTX-II Chemical Structure

PLTX-II Chemical Structure

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Description

PLTX-II is a calcium channel blocker. PLTX-II has a 44-residue peptide containing ten Cys residues and an O-palmitoylated threonine amide at the carboxy-terminus[1].

Molecular Weight

5108.73

Formula

C208H313N61O70S10

Sequence

Ala-Asp-Cys-Ser-Ala-Thr-Gly-Asp-Thr-Cys-Asp-His-Thr-Lys-Lys-Cys-Cys-Asp-Asp-Cys-Tyr-Thr-Cys-Arg-Cys-Gly-Thr-Pro-Trp-Gly-Ala-Asn-Cys-Arg-Cys-Asp-Tyr-Tyr-Lys-Ala-Arg-Cys-Asp-{Thr(O-palmitoyl)}-NH2 (Disulfide bridge: Cys3-Cys17,Cys10-Cys23,Cys16-Cys35,Cys20-Cys42,Cys25-Cys33)

Sequence Shortening

ADCSATGDTCDHTKKCCDDCYTCRCGTPWGANCRCDYYKARCD-{Thr(O-palmitoyl)}-NH2 (Disulfide bridge: Cys3-Cys17,Cys10-Cys23,Cys16-Cys35,Cys20-Cys42,Cys25-Cys33)

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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PLTX-II
Cat. No.:
HY-P5954
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