2. Anti-infection
  3. Fungal
  4. (+)-Magnoflorine chloride

(+)-Magnoflorine chloride  (Synonyms: Magnoflorine chloride; α-Magnoflorine chloride; Thalictrine chloride)

Cat. No.: HY-N0535 Purity: 99.29%
COA Handling Instructions

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Magnoflorine chloride (Magnoflorine chloride), an aporphine alkaloid found in Magnolia or Aristolochia, reduces the formation of C. albicans biofilm. Magnoflorine chloride has anti-fungal, anti-antidiabetic and anti-oxidative activity.

For research use only. We do not sell to patients.

(+)-Magnoflorine chloride Chemical Structure

(+)-Magnoflorine chloride Chemical Structure

CAS No. : 6681-18-1

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1 mg USD 30 In-stock
5 mg USD 50 In-stock
10 mg USD 75 In-stock
25 mg USD 135 In-stock
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Based on 1 publication(s) in Google Scholar

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(+)-Magnoflorine chloride Related Antibodies

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Description

Magnoflorine chloride (Magnoflorine chloride), an aporphine alkaloid found in Magnolia or Aristolochia, reduces the formation of C. albicans biofilm[1]. Magnoflorine chloride has anti-fungal, anti-antidiabetic and anti-oxidative activity[2].

Molecular Weight

377.86

Formula

C20H24ClNO4
CAS No.
Appearance

Solid

Color

Yellow to brown

SMILES

OC1=C(C2=C3O)C([C@]([N+]4(C)C)([H])CC2=CC=C3OC)=C(CC4)C=C1OC.[Cl-]
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

H2O : 41.67 mg/mL (110.28 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6465 mL 13.2324 mL 26.4648 mL
5 mM 0.5293 mL 2.6465 mL 5.2930 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (264.65 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.29%

COA (255 KB) HNMR (122 KB) LCMS (92 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.6465 mL 13.2324 mL 26.4648 mL 66.1621 mL
5 mM 0.5293 mL 2.6465 mL 5.2930 mL 13.2324 mL
10 mM 0.2646 mL 1.3232 mL 2.6465 mL 6.6162 mL
15 mM 0.1764 mL 0.8822 mL 1.7643 mL 4.4108 mL
20 mM 0.1323 mL 0.6616 mL 1.3232 mL 3.3081 mL
25 mM 0.1059 mL 0.5293 mL 1.0586 mL 2.6465 mL
30 mM 0.0882 mL 0.4411 mL 0.8822 mL 2.2054 mL
40 mM 0.0662 mL 0.3308 mL 0.6616 mL 1.6541 mL
50 mM 0.0529 mL 0.2646 mL 0.5293 mL 1.3232 mL
60 mM 0.0441 mL 0.2205 mL 0.4411 mL 1.1027 mL
80 mM 0.0331 mL 0.1654 mL 0.3308 mL 0.8270 mL
100 mM 0.0265 mL 0.1323 mL 0.2646 mL 0.6616 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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(+)-Magnoflorine chloride Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(+)-Magnoflorine6681-18-1Magnoflorineα-MagnoflorineThalictrineFungalAporphinealkaloidAcoruscalamusC.albicansbiofilm anti-fungalanti-antidiabeticanti-oxidativeInhibitorinhibitorinhibit

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