(+)-Perillyl alcohol (Synonyms: (R)-(+)-Perillyl alcohol)

Cat. No.: HY-W747572: FAQs
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(+)-Perillyl alcohol is the enantiomer of S-(-)-Perillyl alcohol (HY-116514). (+)-Perillyl alcohol can inhibit the growth of polypeptides and block the cell cycle in the G0/G1 phase. (+)-Perillyl alcohol induces cell signaling that is associated with changes in cytoskeletal actin organization and reduced protein expression of growth regulatory proteins such as Ras and CDC2 kinase.

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(+)-Perillyl alcohol Chemical Structure

CAS No. : 57717-97-2

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Description	(+)-Perillyl alcohol is the enantiomer of S-(-)-Perillyl alcohol (HY-116514). (+)-Perillyl alcohol can inhibit the growth of polypeptides and block the cell cycle in the G0/G1 phase. (+)-Perillyl alcohol induces cell signaling that is associated with changes in cytoskeletal actin organization and reduced protein expression of growth regulatory proteins such as Ras and CDC2 kinase^[1].
In Vitro	(+)-Perillyl alcohol (0.25-1 mM) inhibits cell growth in SW480 cells^[1]. (+)-Perillyl alcohol (1 mM; 24 h) increases the number of G0/G1 cells and decreases the number of S phase cells in SW480 cells^[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. (+)-Perillyl alcohol Related Antibodies
Molecular Weight	152.23
Formula	C₁₀H₁₆O
CAS No.	57717-97-2
SMILES	CC([C@@H]1CCC(CO)=CC1)=C
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (265 KB) Handling Instructions (2659 KB)
References	[1]. Cerda SR, et al. R-(+)-perillyl alcohol-induced cell cycle changes, altered actin cytoskeleton, and decreased ras and p34(cdc2) expression in colonic adenocarcinoma SW480 cells. J Nutr Biochem. 1999 Jan;10(1):19-30. [Content Brief]

(+)-Perillyl alcohol Related Classifications

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(+)-Perillyl alcohol57717-97-2(R)-(+)-Perillyl alcoholRasSW480S-(-)-perillyl alcoholInhibitorinhibitorinhibit

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